Thrombomodulin anticorps (AA 69-194)
Aperçu rapide pour Thrombomodulin anticorps (AA 69-194) (ABIN6294573)
Antigène
Voir toutes Thrombomodulin (THBD) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 69-194
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Fonction
- Mouse anti-Human Thrombomodulin Antibody / CD141 [Sodium Azide Free]
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Specificité
- Cell surface, cytoplasmic
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Purification
- Human recombinant partial protein corresponding to amino acids 69-194 was used as the immunogen for this Thrombomodulin antibody.
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Immunogène
- Human recombinant partial protein corresponding to amino acids 69-194 was used as the immunogen for this Thrombomodulin antibody.
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Indications d'application
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FACS: 0.5-1 μg/10^6 cells in 0.1ml
IF: 0.5-1 μg/mL
IHC (FFPE): 1-2 μg/mL for 30 min at RT,ELISA: 2-4 μg/mL, order the BSA-free formulation for coating -
Restrictions
- For Research Use only
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Buffer
- In 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Thrombomodulin (THBD)
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Autre désignation
- Thrombomodulin
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Sujet
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Target Description: It recognizes a protein of 75 kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi s sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.
Gene Symbol: THBD///THRM
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ID gène
- 7056
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UniProt
- P07204
Antigène
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